SAS code

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libname mydata "/courses/u_coursera.org1/i_1006328/c_5333" access=readonly;

DATA new; set mydata.nesarc_pds;

/*major depressive disorder ~ Sex, average daily quantity of alcohol consumed and cigarettes smoked in past 12 months, and use of sedatives, tranquilizers, cannabis, opioids, amphetamines, cocaine, heroine, hallucinogens, and inhalants*/

LABEL MAJORDEPLIFE="major depressive disorder (lifetime)"
SEX="biological sex"
S2AQ8B="alcohol consumed daily" 
S3AQ3C1="cigarettes smoked in past 12 months"
S3BQ1A1="use of sedatives"
S3BQ1A2="use of  tranquilizers"
S3BQ1A3="use of opioids"
S3BQ1A4="use of amphetamines"
S3BQ1A5="use of cannabis"
S3BQ1A6= "use of cocaine"
S3BQ1A7= "use of hallucinogens"
S3BQ1A8= "use of inhalants"
S3BQ1A9A="use of heroin";

/* DATA MUNGING */

/* for the  following variables: alcohol consumed, cigarettes smoked */
 /* change [9] to [NA] */

IF S2AQ8B=99 THEN S2AQ8B=.; /*alcohol*/
IF S3AQ3C1=99 THEN S3AQ3C1=.; /*cigarette*/

/* for the  following variables: "sex", "sedatives", "tranquilizers", "cannabis", "opioids", "amphetamines", "cocaine", "heroine", "hallucinogens", "inhalants" */
 /* change the binomial setting [1,2] --> [1,0] */
 /* change [9] to [NA] */

IF SEX=2 THEN SEX=0;

IF S3BQ1A1=2 THEN S3BQ1A1=0;
IF S3BQ1A2=2 THEN S3BQ1A2=0;
IF S3BQ1A3=2 THEN S3BQ1A3=0;
IF S3BQ1A4=2 THEN S3BQ1A4=0;
IF S3BQ1A5=2 THEN S3BQ1A5=0;
IF S3BQ1A6=2 THEN S3BQ1A6=0;
IF S3BQ1A7=2 THEN S3BQ1A7=0;
IF S3BQ1A8=2 THEN S3BQ1A8=0;
IF S3BQ1A9A=2 THEN S3BQ1A9A=0;

IF S3BQ1A1=9 THEN S3BQ1A1=.;
IF S3BQ1A2=9 THEN S3BQ1A2=.;
IF S3BQ1A3=9 THEN S3BQ1A3=.;
IF S3BQ1A4=9 THEN S3BQ1A4=.;
IF S3BQ1A5=9 THEN S3BQ1A5=.;
IF S3BQ1A6=9 THEN S3BQ1A6=.;
IF S3BQ1A7=9 THEN S3BQ1A7=.;
IF S3BQ1A8=9 THEN S3BQ1A8=.;
IF S3BQ1A9A=9 THEN S3BQ1A9A=.;

IF S3AQ3B1=9 THEN S3AQ3B1=.;
IF S3AQ3C1=99 THEN S3AQ3C1=.;

IF S2AQ8A=99 THEN S2AQ8A=.;
IF S2AQ8B=99 THEN S2AQ8B=.;

/* DATA BINNING - from QUANTITATIVE to CATEGORICAL BINS */

/*SMOKE = from FREQUENCY IN DAYS converted to NUMBER OF DAYS PER YEAR (days per year) */
IF S3AQ3B1= 1 THEN SMOKEFREQYR = 364;
ELSE IF S3AQ3B1= 2 THEN SMOKEFREQYR = 286;
ELSE IF S3AQ3B1= 3 THEN SMOKEFREQYR = 182;
ELSE IF S3AQ3B1= 4 THEN SMOKEFREQYR = 78;
ELSE IF S3AQ3B1= 5 THEN SMOKEFREQYR = 30;
ELSE IF S3AQ3B1= 6 THEN SMOKEFREQYR = 1;

/* assign NEW VARIABLE pack-years */
CIGSPERYEAR = SMOKEFREQYR * S3AQ3C1;

/* ALCOHOL = from FREQUENCY IN DAYS converted to NUMBER OF DAYS PER YEAR (days per year) */
IF S2AQ8A= 1 THEN ALCOHOLFREQYR = 364;
ELSE IF S2AQ8A= 2 THEN ALCOHOLFREQYR = 286;
ELSE IF S2AQ8A= 3 THEN ALCOHOLFREQYR = 182;
ELSE IF S2AQ8A= 4 THEN ALCOHOLFREQYR = 104;
ELSE IF S2AQ8A= 5 THEN ALCOHOLFREQYR = 52;
ELSE IF S2AQ8A= 6 THEN ALCOHOLFREQYR = 30;
ELSE IF S2AQ8A= 7 THEN ALCOHOLFREQYR = 12;
ELSE IF S2AQ8A= 8 THEN ALCOHOLFREQYR = 9;
ELSE IF S2AQ8A= 9 THEN ALCOHOLFREQYR = 4.5;
ELSE IF S2AQ8A= 10 THEN ALCOHOLFREQYR = 1.5;

/* assign NEW VARIABLE drink-years */
SWIGSPERYEAR = ALCOHOLFREQYR * S2AQ8B;

/*make bins for quantitative explanatory variables cigsperyear */
if CIGSPERYEAR LE 2002 then G4CIGS =1001.5;
else if CIGSPERYEAR LE 4550 then G4CIGS = 3276; 
else if CIGSPERYEAR LE 7644 then G4CIGS =6097; 
else if CIGSPERYEAR GT 7644 then G4CIGS =21658; 

/*make bins for quantitative explanatory variables swigsperyear */

if SWIGSPERYEAR LE 10.5 then G4SWIGS = 6;
else if SWIGSPERYEAR LE 63 then G4SWIGS = 36.75; 
else if SWIGSPERYEAR LE 360 then G4SWIGS =211.5; 
else if SWIGSPERYEAR GT 360 then G4SWIGS =35852; 

/*sort tables by row identifier*/
PROC SORT; by IDNUM;

/*PROC ANOVA; CLASS MAJORDEPLIFE;
MODEL AGE=MAJORDEPLIFE;
MEANS MAJORDEPLIFE /TUKEY;*/

/*PROC ANOVA; CLASS G4CIGS;
MODEL AGE=G4CIGS;
MEANS G4CIGS /TUKEY;*/

/*PROC ANOVA; CLASS G4SWIGS;
MODEL AGE=G4SWIGS;
MEANS G4SWIGS /DUNCAN;*/

/*print each observation with the following variables in columns */
/*PROC PRINT; VAR MAJORDEPLIFE SEX  G4CIGS G4SWIGS S3BQ1A1 S3BQ1A2 S3BQ1A3 S3BQ1A4 S3BQ1A5 S3BQ1A6 S3BQ1A7 S3BQ1A8 S3BQ1A9A*/ ;

/*check center, spread, shape*/
/*PROC UNIVARIATE; VAR  G4CIGS G4SWIGS MAJORDEPLIFE SEX S3BQ1A1 S3BQ1A2 S3BQ1A3 S3BQ1A4 S3BQ1A5 S3BQ1A6 S3BQ1A7 S3BQ1A8 S3BQ1A9A*/ ;

/*check frequency tables*/
/*PROC FREQ; TABLES MAJORDEPLIFE SEX G4CIGS G4SWIGS S2AQ8B S3AQ3C1 S3BQ1A1 S3BQ1A2 S3BQ1A3 S3BQ1A4 S3BQ1A5 S3BQ1A6 S3BQ1A7 S3BQ1A8 S3BQ1A9A*/ ;

RUN;

/*get multiple pairwise tables for chi-squared test*/

/*this is for comparing G4CIGS classes versus majordepressive disorder*/
/*Bonferonni correction is 0.05 divided by 6 equals 0.008333333 */

DATA CIGSCOMPARISON1; set NEW;
IF G4CIGS=1001.5 or G4CIGS=3276;
PROC SORT; by IDNUM;

PROC FREQ; TABLES  MAJORDEPLIFE*G4CIGS /CHISQ;

RUN;

DATA CIGSCOMPARISON2; set NEW;
IF G4CIGS=1001.5 or G4CIGS=6097;
PROC SORT; by IDNUM;

PROC FREQ; TABLES  MAJORDEPLIFE*G4CIGS /CHISQ;

RUN;

DATA CIGSCOMPARISON3; set NEW;
IF G4CIGS=1001.5 or G4CIGS=21658;
PROC SORT; by IDNUM;

PROC FREQ; TABLES  MAJORDEPLIFE*G4CIGS /CHISQ;

RUN;

DATA CIGSCOMPARISON4; set NEW;
IF G4CIGS=3276 or G4CIGS=6097;
PROC SORT; by IDNUM;

PROC FREQ; TABLES  MAJORDEPLIFE*G4CIGS /CHISQ;

RUN;

DATA CIGSCOMPARISON5; set NEW;
IF G4CIGS=3276 or G4CIGS=21658;
PROC SORT; by IDNUM;

PROC FREQ; TABLES  MAJORDEPLIFE*G4CIGS /CHISQ;

RUN;

DATA CIGSCOMPARISON6; set NEW;
IF G4CIGS=6097 or G4CIGS=21658;
PROC SORT; by IDNUM;

PROC FREQ; TABLES  MAJORDEPLIFE*G4CIGS /CHISQ;

RUN;

/*this is for comparing G4SWIGS classes versus majordepressive disorder*/
/*Bonferonni correction is 0.05 divided by 6 equals 0.008333333 */

DATA SWIGSCOMPARISON1; set NEW;
IF G4SWIGS=6 or G4SWIGS=36.75;
PROC SORT; by IDNUM;

PROC FREQ; TABLES  MAJORDEPLIFE*G4SWIGS /CHISQ;

RUN;

DATA SWIGSCOMPARISON2; set NEW;
IF G4SWIGS=6 or G4SWIGS=211.5;
PROC SORT; by IDNUM;

PROC FREQ; TABLES  MAJORDEPLIFE*G4SWIGS /CHISQ;

RUN;

DATA SWIGSCOMPARISON3; set NEW;
IF G4SWIGS=6 or G4SWIGS=35852;
PROC SORT; by IDNUM;

PROC FREQ; TABLES  MAJORDEPLIFE*G4SWIGS /CHISQ;

RUN;

DATA SWIGSCOMPARISON4; set NEW;
IF G4SWIGS=36.75 or G4SWIGS=211.5;
PROC SORT; by IDNUM;

PROC FREQ; TABLES  MAJORDEPLIFE*G4SWIGS /CHISQ;

RUN;

DATA SWIGSCOMPARISON5; set NEW;
IF G4SWIGS=36.75 or G4SWIGS=35852;
PROC SORT; by IDNUM;

PROC FREQ; TABLES  MAJORDEPLIFE*G4SWIGS /CHISQ;

RUN;

DATA SWIGSCOMPARISON6; set NEW;
IF G4SWIGS=211.5 or G4SWIGS=35852;
PROC SORT; by IDNUM;

PROC FREQ; TABLES  MAJORDEPLIFE*G4SWIGS /CHISQ;

RUN;

/*COMPARE SUBSTANCES versus MDD */
/*for a 2 by 2 case, we are inclined to call the chi square statistic large, if it is larger than 3.841*/
/* you may check out http://math.hws.edu/javamath/ryan/ChiSquare.html for the table of df versus alpha*/
/*p value is simply 0.05, since it's not a multiple pairwise test*/

DATA COMPARISONS; set NEW;
PROC SORT; by IDNUM;

PROC FREQ; TABLES  MAJORDEPLIFE*S3BQ1A1 /CHISQ; /*sedatives*/
PROC FREQ; TABLES  MAJORDEPLIFE*S3BQ1A2 /CHISQ; /*tranq*/
PROC FREQ; TABLES  MAJORDEPLIFE*S3BQ1A3 /CHISQ; /*opioids*/
PROC FREQ; TABLES  MAJORDEPLIFE*S3BQ1A4 /CHISQ; /*amphet*/
PROC FREQ; TABLES  MAJORDEPLIFE*S3BQ1A5 /CHISQ; /*cannabis*/
PROC FREQ; TABLES  MAJORDEPLIFE*S3BQ1A6 /CHISQ; /*cocaine*/
PROC FREQ; TABLES  MAJORDEPLIFE*S3BQ1A7 /CHISQ; /*hallucinogens*/
PROC FREQ; TABLES  MAJORDEPLIFE*S3BQ1A8 /CHISQ; /*inhalants*/
PROC FREQ; TABLES  MAJORDEPLIFE*S3BQ1A9A /CHISQ; /*heroin*/

RUN;

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